Your Immune System is made up of an intricate arrangement of organs, cells, and specialized tissues that operate simultaneously to protect against harmful pathogens; viruses and bacteria. While defending against pathogens, a fully functioning system, in most cases, has the ability to determine between what naturally belongs vs. what is foreign and needs to be eliminated.
Your Innate Immune System is your body’s first line of defense.
- These cells can usually recognize and respond to threats quickly in order to eradicate them.
- This action is non-specific, meaning the cells do not need to first learn how to recognize an invading pathogen before responding. They just innately know how to do their job.
- The presence of antigens creates antibodies within the innate cells, which signal them to move to the site of a challenge by way of the bloodstream.
- The cells then neutralize the pathogen by surrounding and destroying it.
Your neutrophils, for instance, make up around 70% of your immune cell population. These cells do not always recognize certain threats as non-self. They are also short-lived and regenerate every 12-24 hours. Like all the other innate cells in the body, neutrophils do not have long-term memory.
Unlike your Innate Immune System, your
Adaptive Immune System needs time to learn to recognize threats.
- Because of this, it is slower and cannot react instantly in the event of a foreign challenge.
- The B and T cells comprise part of this system.
- This is where acquired immunity creates immunological memory after the first encounter with a specific pathogen.
- The adaptive cells are specially designed to go after specific targets the subsequent time around and respond immediately with rapid efficiency and accuracy.
But what happens when this fascinatingly, proficient biological structure fails or needs a little assistance to effectively function?
That is where Glucan 300® comes in.
- Glucan 300® works with both your innate and adaptive immune cells. Specialized tissue call Peyer’s Patches located in the small intestine absorb the glucan.
- From there M cells transport it to phagocytes that digest and break the glucan into smaller fragments and release soluble glucan molecules.
- This causes chemical messengers called cytokines to be released; indirectly impacting the activation of T and B cells.
- The soluble molecules then bind to CR3 receptors via the complement on macrophages, NK cells, and neutrophils; priming them for activity.
- Through a symbiotic cascade of immunological reactions, the newly primed cells more quickly navigate (chemotaxis) to the site of a foreign challenge.
- With the Glucan 300® already present the primed cells must simply bind to the complement on a pathogenic cell to activate the enhanced killing ability of the innate cells.
Remember how neutrophils don’t always recognize all threats as non-self?
They are now able to target the invader due to antibodies binding to it and attracting complement. The recently equipped cells now attack and annihilate the threat, as if it were yeast, when ordinarily it would not be recognized.